A stalemate between the Premier League’s two heavyweight teams meant no change at the top of the table.
Honours even at the Etihad
Manchester City and Liverpool drew 2-2 in a thrilling encounter at the Etihad, meaning City remain first and the Reds sit second.
Kevin De Bruyne and Gabriel Jesus netted for the hosts while Diogo Jota and Sadio Mane were on hand to score for Liverpool.
Both third-placed Chelsea and fourth placed Tottenham put in clinical displays, thrashing Southampton and Aston Villa respectively.
The Blues won 6-0, with Mason Mount and Timo Werner both scoring twice alongside strikes from Marcos Alonso and Kai Havertz.
For Spurs, Heung-min Son scored a hat-trick to ensure they continued their good form, with Dejan Kulusevski also netting for the north London side.
Damaging defeats for Arsenal, West Ham and Manchester United
Arsenal weren’t as fortunate, losing 2-1 to Brighton and damaging their chances of Champions League qualification.
Goals from Leandro Trossard and Enock Mwepu were enough for the Seagulls, despite Martin Odegaard’s late consolation.
Manchester United also lost their match, falling to a 1-0 defeat against Everton.
Anthony Gordon scored the only goal of the game as the Toffees secured a memorable victory, with United’s hopes of a top four spot fading away.
Another side in the hunt for European football are West Ham, who dropped points after being beaten 2-0 by Brentford.
Second-half strikes from Bryan Mbeumo and Ivan Toney saw the Bees win another London derby.
There was also defeat for Wolves, who were beaten 1-0 by Newcastle and now look like they will have to fight for a Europa League spot.
A Chris Wood penalty saw the Magpies take all three points and move up to 14th in the table.
Down at the bottom
In the relegation battle, Leeds picked up a huge win against fellow strugglers Watford, winning 3-0 at Vicarage Road.
Raphinha, Rodrigo and Jack Harrison were on hand to score for the visitors who moved a step closer to safety.
Norwich kept their hopes of survival alive with a 2-0 win against Burnley.
The bottom placed side comfortably beat the 19th placed Clarets thanks to goals from Pierre Lees-Melou and Teemu Pukki.
Elsewhere in the Premier League
Finally, Leicester City won 2-1 against Crystal Palace.
Goals from Ademola Lookman and Kiernan Dewsbury-Hall were enough for the Foxes, with Wilfred Zaha scoring for Palace.