There’s a huge Manchester derby this weekend alongside some other important games as the fights for European football and to avoid relegation continue.
Manchester City host bitter rivals United in the derby
Manchester City welcome Manchester United, looking to extend their lead at the top of the table with Liverpool chasing behind them.
City are six points clear having played one more game than their title rivals, while United are hanging on to fourth place with teams like West Ham and Arsenal not far behind.
Liverpool face the Hammers off the back of their Carabao Cup triumph against Chelsea and will be hoping to pick up a vital three points in the title race.
A win for their opponents would push them back into the top four.
Chelsea finally return to Premier League action after competing in various other competitions, travelling to relegation-threatened Burnley.
The Blues were unsuccessful in the Carabao Cup final but have the slightly easier task of facing the 18th-placed side this weekend.
North London duo continue their top-four ambitions
Arsenal are also in action against a team battling to avoid the drop in Watford, and a win for the Gunners could see them move into the Champions League places.
They face a Watford side who have struggled all season and are now playing under their third manager of the campaign.
Fellow north London side Tottenham crashed out of the FA Cup during the week and will be looking to bounce back when they face Everton on Monday.
They have improved under Antonio Conte but are still suffering disappointing losses in games they should be winning.
Down at the bottom
Elsewhere, there is a huge match in the fight against relegation, with Norwich welcoming Brentford.
The Canaries sit bottom of the league while the Bees have struggled during 2022 and dropped down to 15th, just three points above the drop zone.
Leeds United have also struggled this year, leading to the sacking of iconic manager Marcelo Bielsa.
He has been replaced by Jesse Marsch, who takes charge of his first game when the Yorkshire club face Leicester City.
There is a top-six push on the cards for Wolves, who have had an impressive season under new coach Bruno Lage.
Their form can continue this weekend when they play Crystal Palace, who have also been impressive in their first season with Patrick Vieira at the helm.
Newcastle are another team that have improve since hiring a new manager, with Eddie Howe getting the best out of his players since the turn of the year.
The Magpies take on Brighton on Saturday in a bid to push further away from the relegation zone.
Finally, Southampton travel to Aston Villa on Saturday, looking to solidify their position in the top half of the league.